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SR 18292是PGC-1α抑制剂。在T2D的饮食和遗传小鼠模型中，它可降低血糖，强烈提高肝胰岛素敏感性并改善葡萄糖稳态。
| In vitro | DMSO | 63 mg/mL (171.9 mM) | |
| Water | Insoluble | ||
| Ethanol | 63 mg/mL (171.9 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.28 mL | 136.42 mL | 272.84 mL |
| 0.5 mM | 5.46 mL | 27.28 mL | 54.57 mL |
| 1 mM | 2.73 mL | 13.64 mL | 27.28 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
*The above data is based on the productmolecular weight 366.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16914 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 366.51 |
| Formula | C23H30N2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2095432-55-4 |
| Synonyms | SR-18292, SR18292 |
| SMILES | CC(C=C1)=CC=C1CN(C(C)(C)C)CC(O)COC2=CC=CC3=C2C=CN3 |
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