SR0987
目录号: A20422
RORγt agonist
SR0987，一种SR1078类似物，是一种RORγt激动剂，具有800 nM的EC50。SR0987增加IL17表达的同时，抑制PD-1的表达。
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生物活性
| Discription | SR0987, a SR1078 analog, is a RORγt agonist, with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1. |
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产品信息
| 目录号 | A20422 |
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| 分子式 | C16H10ClF6NO2 |
| 分子量 | 397.7 |
| CAS号 | 303126-97-8 |
| SMILES | O=C(NC1=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C1)C2=CC=CC=C2Cl |
| 其他名称 | SR 0987, SR-0987 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 74 mg/mL (186.06 mM) | |
| Water | Insoluble | ||
| Ethanol | 37 mg/mL (93.03 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.14 mL | 125.72 mL | 251.45 mL |
| 0.5 mM | 5.03 mL | 25.14 mL | 50.29 mL |
| 1 mM | 2.51 mL | 12.57 mL | 25.14 mL |
| 5 mM | 0.5 mL | 2.51 mL | 5.03 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 303126-97-8 | 303126-97-8 供应商 | 303126-97-8 花费 | 303126-97-8 生产商 | 订购 303126-97-8 | 303126-97-8 代理商