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SR0987

产品详情

生物活性

SR0987, a SR1078 analog, is a RORγt agonist, with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1.

溶解度 *

In vitro	DMSO	74 mg/mL (186.06 mM)
	Water	Insoluble
	Ethanol	37 mg/mL (93.03 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.14 mL	125.72 mL	251.45 mL
0.5 mM	5.03 mL	25.14 mL	50.29 mL
1 mM	2.51 mL	12.57 mL	25.14 mL
5 mM	0.5 mL	2.51 mL	5.03 mL

*The above data is based on the productmolecular weight 397.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20422
M. Wt	397.7
Formula	C16H10ClF6NO2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	303126-97-8
Synonyms	SR 0987, SR-0987
SMILES	O=C(NC1=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C1)C2=CC=CC=C2Cl