STF-083010
STF-083010 是一种特定的 IRE1α 抑制剂。STF-083010 在内质网应激后抑制 Ire1 的核酸内切酶活性,但不影响其激酶活性。
Discription | STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress. |
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目录号 | A16720 |
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分子式 | C15H11NO3S2 |
分子量 | 317.38 |
CAS号 | 307543-71-1 |
SMILES | O=S(C1=CC=CS1)(/N=C/C2=C3C=CC=CC3=CC=C2O)=O |
其他名称 | STF083010, STF 083010 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 54 mg/mL (170.14 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+40%PEG 300+5% Tween80 +ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 31.51 mL | 157.54 mL | 315.08 mL |
0.5 mM | 6.3 mL | 31.51 mL | 63.02 mL |
1 mM | 3.15 mL | 15.75 mL | 31.51 mL |
5 mM | 0.63 mL | 3.15 mL | 6.3 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2