STF 118804
目录号: A14072
NAMPT 抑制剂
STF 118804 是一种高度特异性的 NAMPT 抑制剂，能够在低纳摩尔范围内的高效 IC50 值降低大多数 B-ALL 细胞系的存活率，并在高风险急性淋巴细胞性白血病的原位异种移植模型中改善存活率。
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生物活性
| Discription | STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia. | |||||
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| Cell Research |
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产品信息
| 目录号 | A14072 |
|---|---|
| 分子式 | C25H23N3O4S |
| 分子量 | 461.53 |
| CAS号 | 894187-61-2 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)CC2=C(OC(=N2)C3=CC=C(C=C3)C(=O)NCC4=CN=CC=C4)C |
| 其他名称 | STF118804, STF-118804 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 53 mg/mL (114.83 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.67 mL | 108.34 mL | 216.67 mL |
| 0.5 mM | 4.33 mL | 21.67 mL | 43.33 mL |
| 1 mM | 2.17 mL | 10.83 mL | 21.67 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.33 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 STF 118804 | STF 118804 供应商 | STF 118804 花费 | STF 118804 生产商 | 订购 STF 118804 | STF 118804 代理商
| 购买 894187-61-2 | 894187-61-2 供应商 | 894187-61-2 花费 | 894187-61-2 生产商 | 订购 894187-61-2 | 894187-61-2 代理商