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Streptozotocin (Zanosar)

目录号: A10868
O-GlcNAcase 抑制剂
Streptozotocin(又名Streptozocin、Zanosar、STZ)在医学研究中用于制造1型糖尿病的动物模型,它直接抑制体外酶NCOAT的O-GlcNAcase活性。
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规格 价格 库存 数量
50mg
¥175.00
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100mg
¥245.00
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500mg
¥455.00
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1g
¥840.00
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10mM * 1mL in DMSO
¥210.00
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Streptozotocin (Zanosar)发表的10篇文献
  • Zhen Liang, .et al. , Nat Metab, 2023, Jan;5(1):29-40 PMID: 36624157
  • Alemayehu Toma, .et al. , J Exp Pharmacol, 2022, 14: 309-316 PMID: 36317069
  • Andressa Braga, .et al. , Braz J Pharm Sci, 2022, 58: e19674
  • Yuanyuan Du, .et al. , Nat Med, 2022, Feb;28(2):272-282 PMID: 35115708
  • Karemah A. Alatawi, .et al. , Saudi Journal of Biological Sciences, 2021, 25 June
  • D.H. Mhya, .et al. , Asian J Exp Biol Sci, 2019, 12 (2): 164-172
  • Stanley I. R. Okoduwa, .et al. , J Diabetol, 2017, 8(3): 74-85
  • Stanley I. R. Okoduwa, .et al. , Medicines (Basel), 2017, Dec; 4(4): 73 PMID: 29019956
  • Stanley I. R. Okoduwa, .et al. , PLoS One, 2017, 12(1): e0170971 PMID: 28129400
  • Stanley I. R. Okoduwa, .et al. , World J Diabetes, 2016, Dec 15; 7(20): 605-614 PMID: 28031778
  • 生物活性
    Discription Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.
    产品信息
    目录号 A10868
    分子式 C8H15N3O7
    分子量 265.2
    CAS号 18883-66-4
    SMILES CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O
    其他名称 Streptozocin, Zanosar, STZ
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 51 mg/mL (192.29 mM)
    Water 51 mg/mL (192.29 mM)
    Ethanol Insoluble
    In vivo Saline 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 37.71 mL 188.54 mL 377.07 mL
    0.5 mM 7.54 mL 37.71 mL 75.41 mL
    1 mM 3.77 mL 18.85 mL 37.71 mL
    5 mM 0.75 mL 3.77 mL 7.54 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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