Sunitinib Malate

Name: Sunitinib Malate
SKU: A10880
Price: 210 CNY
Rating: 5 (7 reviews)

目录号: A10880

RTK 抑制剂

7 篇发表文献

舒尼替尼是一种口服的小分子多靶点受体酪氨酸激酶（RTK）抑制剂，用于治疗肾细胞癌（RCC）和对伊马替尼耐药的胃肠间质瘤（GIST）。

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Grouped product items
规格	价格	库存
50mg	¥210.00	现货
100mg	¥315.00	现货
200mg	¥385.00	现货
500mg	¥490.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Sunitinib Malate

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Sunitinib Malate发表的7篇文献

Sophie J. Bakri, .et al. , PLoS One, 2024, 19(6): e0304782 PMID: 38833447

Chern Ein Oon, .et al. , World J Gastrointest Oncol, 2023, May 15;15(5):810-827 PMID: 37275453

Rachel K Toth, .et al. , Cells, 2022, Mar 16;11(6):1006 PMID: 35326457

Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Thibaut Fourniols, .et al. , Int J Pharm, 2020, Jun 30;584:119337 PMID: 32371002

Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961

Brittany M. Duggan, .et al. , Sci Rep, 2017, 7: 1578 PMID: 28484277

生物活性

Discription

Sunitinib is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10880
分子式	C22H27FN4O2.C4H6O5
分子量	532.6
CAS号	341031-54-7
SMILES	CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C.C([C@@H](C(=O)O)O)C(=O)O
其他名称	SU-11248
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	13 mg/mL (24.41 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.78 mL	93.88 mL	187.76 mL
0.5 mM	3.76 mL	18.78 mL	37.55 mL
1 mM	1.88 mL	9.39 mL	18.78 mL
5 mM	0.38 mL	1.88 mL	3.76 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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