Sunitinib
Sunitinib（SU 11248）是一种多靶点受体酪氨酸激酶抑制剂，其对VEGFR2和PDGFRβ的IC50分别为80 nM和2 nM。
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重要通知：仅供研究使用。我们不向患者销售。
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Adooq用户使用Sunitinib发表的2篇文献
生物活性
| Discription | Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. | |||||
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| Cell Research |
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产品信息
| 目录号 | A17858 |
|---|---|
| 分子式 | C22H27FN4O2 |
| 分子量 | 398.47 |
| CAS号 | 557795-19-4 |
| SMILES | O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C |
| 其他名称 | SU 11248, SU11248, SU-11248 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | Warmed: 23 mg/mL (57.71 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+corn oil | 0.83 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.1 mL | 125.48 mL | 250.96 mL |
| 0.5 mM | 5.02 mL | 25.1 mL | 50.19 mL |
| 1 mM | 2.51 mL | 12.55 mL | 25.1 mL |
| 5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 557795-19-4 | 557795-19-4 供应商 | 557795-19-4 花费 | 557795-19-4 生产商 | 订购 557795-19-4 | 557795-19-4 代理商