T863

目录号: A11386
DGAT1 inhibitor
T863 是一种口服活性、选择性和高效的 DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) 抑制剂,它与 DGAT1 的 acyl-CoA 结合位点相互作用,并抑制细胞中的三酰甘油合成。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
2mg
¥280.00
现货
5mg
¥455.00
现货
10mg
¥700.00
现货
25mg
¥1,645.00
现货
50mg
¥2,520.00
现货
100mg
¥4,095.00
现货
10mM * 1mL in DMSO
¥525.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A11386
分子式 C22H26N4O3
分子量 394.47
CAS号 701232-20-4
SMILES O=C(O)C[C@H]1CC[C@H](C2=CC=C(C3=NC4=C(N)N=CN=C4OC3(C)C)C=C2)CC1
其他名称 T 863, T-863
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 73 mg/mL (185.05 mM)
Water Insoluble
Ethanol 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.35 mL 126.75 mL 253.5 mL
0.5 mM 5.07 mL 25.35 mL 50.7 mL
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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