T863
目录号: A11386
DGAT1 inhibitor
T863 是一种口服活性、选择性和高效的 DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) 抑制剂,它与 DGAT1 的 acyl-CoA 结合位点相互作用,并抑制细胞中的三酰甘油合成。
Discription | T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A11386 |
---|---|
分子式 | C22H26N4O3 |
分子量 | 394.47 |
CAS号 | 701232-20-4 |
SMILES | O=C(O)C[C@H]1CC[C@H](C2=CC=C(C3=NC4=C(N)N=CN=C4OC3(C)C)C=C2)CC1 |
其他名称 | T 863, T-863 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 73 mg/mL (185.05 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.35 mL | 126.75 mL | 253.5 mL |
0.5 mM | 5.07 mL | 25.35 mL | 50.7 mL |
1 mM | 2.54 mL | 12.68 mL | 25.35 mL |
5 mM | 0.51 mL | 2.54 mL | 5.07 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2