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TAK-659

目录号: A20450
SYK/FLT3 抑制剂
TAK-659 是一种高效、选择性、可逆转且可口服的双重抑制剂,针对脾脏酪氨酸激酶(SYK)和fms相关酪氨酸激酶3(FLT3),其半抑制浓度(IC50)分别为3.2 nM和4.6 nM。
Grouped product items
规格 价格 库存 数量
5mg
¥840.00
现货
10mg
¥1,470.00
现货
25mg
¥2,380.00
现货
50mg
¥4,340.00
现货
100mg
¥8,260.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A20450
分子式 C17H21FN6O
分子量 344.39
CAS号 1312691-33-0
SMILES FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O
其他名称 TAK659, TAK 659
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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