TAK-659
目录号: A20450
SYK/FLT3 抑制剂
TAK-659 是一种高效、选择性、可逆转且可口服的双重抑制剂,针对脾脏酪氨酸激酶(SYK)和fms相关酪氨酸激酶3(FLT3),其半抑制浓度(IC50)分别为3.2 nM和4.6 nM。
Discription | TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. | |||||
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Cell Research |
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目录号 | A20450 |
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分子式 | C17H21FN6O |
分子量 | 344.39 |
CAS号 | 1312691-33-0 |
SMILES | FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O |
其他名称 | TAK659, TAK 659 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2