TAK-715

Name: TAK-715
SKU: A11582
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A11582

p38 MAPK 抑制剂

1 篇发表文献

TAK 715 是一种 p38 MAPK 抑制剂（对 p38 MAPKα 的 IC50 = 7.1 nM），抑制 Wnt/β-catenin 信号传导，并且能够抑制包括 CK 1δ/ε 在内的 22 种激酶超过 80%。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥490.00	现货
10mg	¥665.00	现货
25mg	¥1,190.00	现货
50mg	¥2,205.00	现货
100mg	¥3,675.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用TAK-715发表的1篇文献

Dongdong Fang, etc. Epithelial-Mesenchymal Transition of Ovarian Cancer Cells Is Sustained by Rac1 through Simultaneous Activation of MEK1/2 and Src Signaling Pathways. Oncogene. 2017 Mar; 36(11): 1546?€?1558.

生物活性

Discription

TAK 715 an inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα), Wnt/beta-catenin signaling, and Inhibits 22 kinases by more than 80%, including CK 1δ/ε.

Targets

Target	Value

产品信息

目录号	A11582
分子式	C24H21N3OS
分子量	399.51
CAS号	303162-79-0
SMILES	CCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)C3=CC=CC=C3)C4=CC(=CC=C4)C
其他名称	TAK715, TAK 715
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	72 mg/mL (180.22 mM)
	Water	Insoluble
	Ethanol	14 mg/mL (35.04 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.03 mL	125.15 mL	250.31 mL
0.5 mM	5.01 mL	25.03 mL	50.06 mL
1 mM	2.5 mL	12.52 mL	25.03 mL
5 mM	0.5 mL	2.5 mL	5.01 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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