TAK-901

Name: TAK-901
SKU: A11067
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A11067

Aurora Kinase A/B 抑制剂

TAK-901 是一种新型的 Aurora A/B 抑制剂，其 IC50 分别为 21 nM 和 15 nM。它不是细胞 JAK2、c-Src 或 Abl 的有效抑制剂。目前处于 第一阶段 临床试验。

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Grouped product items
规格	价格	库存
5mg	¥385.00	现货
10mg	¥735.00	现货
25mg	¥1,540.00	现货
50mg	¥2,625.00	现货
100mg	¥4,725.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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Data Sheet

SDS

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生物活性

Discription

TAK-901 is a novel inhibitor of Aurora A/B with IC50 of 21 nM/15 nM. It is not a potent inhibitor of cellular JAK2, c-Src or Abl. Phase 1.

Targets

Target	Value

产品信息

目录号	A11067
分子式	C28H32N4O3S
分子量	504.6
CAS号	934541-31-8
SMILES	CCS(=O)(=O)C1=CC=CC(=C1)C2=CC(=C(C3=C2C4=CC(=CN=C4N3)C)C)C(=O)NC5CCN(CC5)C
其他名称	TAK901
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	95 mg/mL (188.25 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO +30% PEG 300+2% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.82 mL	99.09 mL	198.18 mL
0.5 mM	3.96 mL	19.82 mL	39.64 mL
1 mM	1.98 mL	9.91 mL	19.82 mL
5 mM	0.4 mL	1.98 mL	3.96 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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