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TAK-960 hydrochloride

目录号: A21703
PLK1 抑制剂
TAK-960 氢氯化物是一种口服可用的、选择性的 polo-like kinase 1 (PLK1) 抑制剂,其在 10 μM ATP 下的 IC50 为 0.8 nM;TAK-960 氢氯化物还显示出对 PLK2PLK3 的抑制活性,其 IC50 分别为 16.9 nM 和 50.2 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥385.00
现货
5mg
¥1,085.00
现货
10mg
¥1,540.00
现货
25mg
¥2,730.00
现货
50mg
¥4,725.00
现货
100mg
¥7,350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription TAK-960 hydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM at 10 μM ATP; TAK-960 hydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively.
Targets
Target Value
产品信息
目录号 A21703
分子式 C27H35ClF3N7O3
分子量 598.06
CAS号 1137868-96-2
SMILES CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2F)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC.Cl
其他名称 TAK 960, TAK960
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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