Takinib
目录号: A16960
TAK1 抑制剂
Takinib 是一种选择性的 TAK1 抑制剂，在类风湿性关节炎和转移性乳腺癌的细胞模型中，TNF-α 刺激后诱导凋亡。
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生物活性
| Discription | Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. | ||
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| Targets |
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产品信息
| 目录号 | A16960 |
|---|---|
| 分子式 | C18H18N4O2 |
| 分子量 | 322.36 |
| CAS号 | 1111556-37-6 |
| SMILES | O=C(C1=CC=CC(C(NC2=NC3=CC=CC=C3N2CCC)=O)=C1)N |
| 其他名称 | EDHS-206, EDHS 206, EDHS206 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 61 mg/mL (189.22 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.02 mL | 155.11 mL | 310.21 mL |
| 0.5 mM | 6.2 mL | 31.02 mL | 62.04 mL |
| 1 mM | 3.1 mL | 15.51 mL | 31.02 mL |
| 5 mM | 0.62 mL | 3.1 mL | 6.2 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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