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Talarozole

目录号: A21124

CYP26 抑制剂/RAMBA

Talarozole (R115866) 是一种口服系统性全反式维甲酸代谢阻断剂(RAMBA),它可以增加细胞内源性全反式维甲酸(RA)的水平。Talarozole 抑制 CYP26A1 和 CYP26B1,其 IC50 分别为 5.4 和 0.46 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥420.00
现货
2mg
¥700.00
现货
5mg
¥910.00
现货
10mg
¥1,190.00
现货
25mg
¥1,680.00
现货
50mg
¥2,205.00
现货
100mg
¥3,360.00
现货
10mM * 1mL in DMSO
¥735.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A21124
分子式 C21H23N5S
分子量 377.51
CAS号 201410-53-9
SMILES CCC(CC)C(C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4N=CN=C4
其他名称 R115866, R 115866, R-115866
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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