Tandutinib (MLN518)

Name: Tandutinib (MLN518)
SKU: A10887
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A10887

FLT3 抑制剂

Tandutinib (MLN518) 抑制 FLT3、c-KIT 和 PDGF 受体酪氨酸激酶的自磷酸化，从而抑制细胞增殖并诱导凋亡。

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Grouped product items
规格	价格	库存
25mg	¥210.00	现货
50mg	¥315.00	现货
100mg	¥455.00	现货
200mg	¥665.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Tandutinib (MLN518) inhibits the autophosphorylation of FLT3, c-KIT and PDGF receptor tyrosine kinases, thereby inhibiting cellular proliferation and inducing apoptosis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10887
分子式	C31H42N6O4
分子量	562.7
CAS号	387867-13-2
SMILES	CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5
其他名称	MLN-518, CT53518
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	5 mg/mL (8.88 mM)
	Water	Insoluble
	Ethanol	6 mg/mL (10.66 mM)
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.77 mL	88.86 mL	177.71 mL
0.5 mM	3.55 mL	17.77 mL	35.54 mL
1 mM	1.78 mL	8.89 mL	17.77 mL
5 mM	0.36 mL	1.78 mL	3.55 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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