TAS-116

Name: TAS-116
SKU: A20987
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A20987

HSP90α/HSP90β 抑制剂

TAS-116 是一种口服生物可利用的、ATP竞争性的、高度特异性的 HSP90α/HSP90β 抑制剂（分别为 Kis 34.7 nM 和 21.3 nM），不抑制其他 HSP90 家族蛋白如 GRP94。TAS-116 表现出较低的眼部毒性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥420.00	现货
10mg	¥630.00	现货
25mg	¥1,330.00	现货
50mg	¥2,590.00	现货
100mg	¥5,040.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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Data Sheet

SDS

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生物活性

Discription

TAS-116 is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor (Kis of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94. TAS-116 demonstrates less ocular toxicity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20987
分子式	C25H26N8O
分子量	454.53
CAS号	1260533-36-5
SMILES	O=C(N)C1=CC=C(N2N=C(C(C)C)C3=C(N4C=C(C5=CN(C)N=C5)N=C4)C=CN=C32)C(CC)=C1
其他名称	TAS116, TAS 116
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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