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Taxifolin以很大的结合能值结合在VEGFR-2激酶的ATP结合位点上，并起I型竞争性抑制剂的作用。
靶点信息
| In vitro | DMSO | 56 mg/mL (184.05 mM) | |
| Water | Insoluble | ||
| Ethanol | 56 mg/mL (184.05 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.86 mL | 164.31 mL | 328.62 mL |
| 0.5 mM | 6.57 mL | 32.86 mL | 65.72 mL |
| 1 mM | 3.29 mL | 16.43 mL | 32.86 mL |
| 5 mM | 0.66 mL | 3.29 mL | 6.57 mL |
*The above data is based on the productmolecular weight 304.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10893 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 304.3 |
| Formula | C15H12O7 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 480-18-2 |
| Synonyms | Dihydroquercetin, Taxifoliol, Distylin, Catechin hydrate, (+)-Taxifolin, trans-Dihydroquercetin, (+)-Dihydroquercetin |
| SMILES | C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O |
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