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Tazemetostat hydrobromide (EPZ-6438 hydrobromide) is a potent, selective and orally available EZH2 inhibitor.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.3 mL | 76.49 mL | 152.99 mL |
| 0.5 mM | 3.06 mL | 15.3 mL | 30.6 mL |
| 1 mM | 1.53 mL | 7.65 mL | 15.3 mL |
| 5 mM | 0.31 mL | 1.53 mL | 3.06 mL |
*The above data is based on the productmolecular weight 653.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21759 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 653.65 |
| Formula | C34H45BrN4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1467052-75-0 |
| Synonyms | EPZ-6438 hydrobromide, EPZ6438, EPZ 6438; E-7438 hydrobromide, E 7438, E7438 |
| SMILES | O=C(C1=CC(C2=CC=C(CN3CCOCC3)C=C2)=CC(N(CC)C4CCOCC4)=C1C)NCC5=C(C)C=C(C)NC5=O.[H]Br |
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