TBK1/IKKε-IN-5
目录号: A18400
dual TBK1 and IKKε 抑制剂
TBK1/IKKε-IN-5 是一种同时针对 TBK1 和 IKKε 的双重抑制剂,其 IC50 值分别为 TBK1 的 1 nM 和 IKKε 的 5.6 nM。
Discription | TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively. |
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目录号 | A18400 |
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分子式 | C28H31N7O3 |
分子量 | 513.59 |
CAS号 | 1893397-65-3 |
SMILES | N#CC1=CC(C2=NC(NC3=CC=C(N4CCN(C5COC5)CC4)C=C3)=NC=N2)=CC=C1OC6CCOCC6 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 9 mg/mL (17.52 mM) | |
Water | <1 mg/mL | ||
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.47 mL | 97.35 mL | 194.71 mL |
0.5 mM | 3.89 mL | 19.47 mL | 38.94 mL |
1 mM | 1.95 mL | 9.74 mL | 19.47 mL |
5 mM | 0.39 mL | 1.95 mL | 3.89 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2