产品详情
TC-E 5001是双重tankyrase(TNKS)抑制剂(TNKS1和TNKS2的Kd值分别为79和28 nM,TNKS2的IC50 = 33 nM),在PARP1和PARP2上没有活性(IC50> 19 uM)。抑制Wnt信号并稳定Axin2水平。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.42 mL | 122.11 mL | 244.22 mL |
0.5 mM | 4.88 mL | 24.42 mL | 48.84 mL |
1 mM | 2.44 mL | 12.21 mL | 24.42 mL |
5 mM | 0.49 mL | 2.44 mL | 4.88 mL |
*The above data is based on the productmolecular weight 409.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11454 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 409.46 |
Formula | C20H19N5O3S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 865565-29-3 |
Synonyms | TC-E5001, TC-E-5001 |
SMILES | CC(N1C(C=C2)=CC=C2OC)=NN=C1SCC3=NC(C(C=C4)=CC=C4OC)=NO3 |
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 TC-E 5001 | TC-E 5001 供应商 | 订购 TC-E 5001 | TC-E 5001 价格 | TC-E 5001 生产商 | 订单 TC-E 5001 | TC-E 5001 代理商 | 购买 865565-29-3| 865565-29-3 供应商 | 订购 865565-29-3 | 865565-29-3 价格 | 865565-29-3 生产商 | 订单 865565-29-3 | 865565-29-3 代理商|buy TC-E 5001 | TC-E 5001 Supplier | purchase TC-E 5001 | TC-E 5001 cost | TC-E 5001 manufacturer | order TC-E 5001 | TC-E 5001 distributor | buy 865565-29-3| 865565-29-3 Supplier | purchase 865565-29-3 | 865565-29-3 cost | 865565-29-3 manufacturer | order 865565-29-3 | 865565-29-3 distributor