TC-E 5001

Name: TC-E 5001
SKU: A11454
Price: 2940 CNY
Rating: 5 (288 reviews)

目录号: A11454

TNKS 抑制剂

TC-E 5001 是一种双重 tankyrase (TNKS) 抑制剂（对 TNKS1 和 TNKS2 的 Kd 值分别为 79 nM 和 28 nM，TNKS2 的 IC50 = 33 nM），不活跃于 PARP1 和 PARP2（IC50 >19 uM）。它能抑制 Wnt 信号传导并稳定 Axin2 水平。

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Grouped product items
规格	价格	库存
5mg	¥2,940.00	现货
10mg	¥5,180.00	现货
25mg	¥10,360.00	现货
50mg	¥13,440.00	现货
100mg	¥17,465.00	现货
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Data Sheet

SDS

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生物活性

Discription

TC-E 5001 is dual tankyrase (TNKS) inhibitor (Kd values are 79 and 28 nM for TNKS1 and TNKS2 respectively, IC50 = 33 nM for TNKS2) that is devoid of activity at PARP1 and PARP2 (IC50 >19 uM). Inhibits Wnt signaling and stabilizes Axin2 levels.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11454
分子式	C20H19N5O3S
分子量	409.46
CAS号	865565-29-3
SMILES	CC(N1C(C=C2)=CC=C2OC)=NN=C1SCC3=NC(C(C=C4)=CC=C4OC)=NO3
其他名称	TC-E5001, TC-E-5001
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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