TC-E 5001

目录号: A11454

TNKS 抑制剂

TC-E 5001

TC-E 5001 Chemical Structure

CAS NO. 865565-29-3

TC-E 5001是双重tankyrase(TNKS)抑制剂(TNKS1和TNKS2的Kd值分别为79和28 nM,TNKS2的IC50 = 33 nM),在PARP1和PARP2上没有活性(IC50> 19 uM)。抑制Wnt信号并稳定Axin2水平。

库存: 现货

规格 价格 数量
5 mg
¥ 560.00
10 mg
¥ 980.00
50 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

TC-E 5001是双重tankyrase(TNKS)抑制剂(TNKS1和TNKS2的Kd值分别为79和28 nM,TNKS2的IC50 = 33 nM),在PARP1和PARP2上没有活性(IC50> 19 uM)。抑制Wnt信号并稳定Axin2水平。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.42 mL 122.11 mL 244.22 mL
0.5 mM 4.88 mL 24.42 mL 48.84 mL
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11454
作用机制 Inhibitor (抑制剂)
M. Wt 409.46
Formula C20H19N5O3S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 865565-29-3
Synonyms TC-E5001, TC-E-5001
SMILES CC(N1C(C=C2)=CC=C2OC)=NN=C1SCC3=NC(C(C=C4)=CC=C4OC)=NO3

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