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TC-I 2014

目录号: A19793
TRPM8 拮抗剂
TC-I 2014(化合物5)是一种有效的、可口服的含苯并咪唑的瞬时受体电位瓜氨酸8型(TRPM8)拮抗剂,其IC50值分别针对犬、人类和大鼠的通道为0.8 nM、3.0 nM和4.4 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥350.00
现货
5mg
¥840.00
现货
10mg
¥1,435.00
现货
25mg
¥2,940.00
现货
50mg
¥4,760.00
现货
100mg
¥7,875.00
现货
200mg
¥10,675.00
现货
10mM * 1mL in DMSO
¥910.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription TC-I 2014 (compound 5) is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A19793
分子式 C23H19F6N3O
分子量 467.41
CAS号 1221349-53-6
SMILES FC(C1=CC=CC=C1C2=CC(C(F)(F)F)=C3C(N=C(C4=NOC5(CCCCC5)C4)N3)=C2)(F)F
其他名称 TC-I2014, TC-I-2014
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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