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TCS PIM-1 4a (SMI-4a)

TCS PIM-1 4a (SMI-4a)

Name: TCS PIM-1 4a (SMI-4a)
SKU: A11967

目录号: A11967

Pim 抑制剂

TCS PIM-1 4a (SMI-4a) Chemical Structure

CAS NO. 438190-29-5

TCS PIM-1 4a (SMI-4a)是一种具有选择性和ATP竞争性的Pim激酶抑制剂（Pim-1和Pim-2的IC50值分别为24和100 nM）。

库存：现货

规格	价格	数量
10 mg	￥ 455.00
25 mg	￥ 1,050.00
50 mg	￥ 1,855.00
10mM * 1mL in DMSO	￥ 574.00

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生物活性

TCS PIM-1 4a (SMI-4a)是一种具有选择性和ATP竞争性的Pim激酶抑制剂（Pim-1和Pim-2的IC50值分别为24和100 nM）。

靶点信息

Pim1
17 nM

溶解度 *

In vitro (25°C)	DMSO	47 mg/mL (172.01 mM)
	Water	Insoluble
	Ethanol	28 mg/mL (102.47 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	36.6 mL	183 mL	365.99 mL
0.5 mM	7.32 mL	36.6 mL	73.2 mL
1 mM	3.66 mL	18.3 mL	36.6 mL
5 mM	0.73 mL	3.66 mL	7.32 mL

*The above data is based on the productmolecular weight 273.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11967
作用机制	Inhibitor (抑制剂)
M. Wt	273.23
Formula	C11H6F3NO2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	438190-29-5
Synonyms	0
SMILES	O=C(NC/1=O)SC1=C\C2=CC=CC(C(F)(F)F)=C2