TD-0212
目录号: A13715
neprilysin (NEP) 抑制剂
TD-0212(化合物35)是一种口服活性的双重药理学药物,具有血管紧张素II型1受体(AT1)拮抗剂和内肽酶(NEP)抑制剂的功能,对AT1的pKi为8.9,对NEP的pIC50为9.2。
Discription | TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP. |
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目录号 | A13715 |
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分子式 | C28H34FN3O4S |
分子量 | 527.65 |
CAS号 | 1073549-10-6 |
SMILES | OC(C1=CC=CC=C1C2=CC=C(CN3C(CNC([C@H](CC(C)C)S)=O)=C(CC)N=C3OCC)C(F)=C2)=O |
其他名称 | TD0212, TD-0212 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2