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TD-106 is a cereblon (CRBN) modulator, which can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.6 mL | 182.98 mL | 365.97 mL |
| 0.5 mM | 7.32 mL | 36.6 mL | 73.19 mL |
| 1 mM | 3.66 mL | 18.3 mL | 36.6 mL |
| 5 mM | 0.73 mL | 3.66 mL | 7.32 mL |
*The above data is based on the productmolecular weight 273.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18595 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 273.25 |
| Formula | C12H11N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2250288-69-6 |
| Synonyms | TD106, TD 106 |
| SMILES | NC1=CC=CC(N=NN2C3CCC(NC3=O)=O)=C1C2=O |
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