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Tegaserod maleate作为运动刺激剂发挥作用，通过激活胃肠道中肠神经系统的5-ht4受体达到其所需的治疗效果。它还能刺激胃肠动力和蠕动反射，据称还能减轻腹痛。此外，替加色罗是5-ht2b受体拮抗剂。
| In vitro | DMSO | 72 mg/mL (172.47 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (16.77 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.95 mL | 119.77 mL | 239.54 mL |
| 0.5 mM | 4.79 mL | 23.95 mL | 47.91 mL |
| 1 mM | 2.4 mL | 11.98 mL | 23.95 mL |
| 5 mM | 0.48 mL | 2.4 mL | 4.79 mL |
*The above data is based on the productmolecular weight 417.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11743 |
|---|---|
| M. Wt | 417.46 |
| Formula | C16H23N5O.C4H4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 189188-57-6 |
| Synonyms | Zelnorm |
| SMILES | CCCCCN=C(N)NN/C=C/1\C=NC2=C1C=C(C=C2)OC.C(=C\C(=O)O)\C(=O)O |
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