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Teijin compound 1 is a specific CCR 2 antagonist with IC50s of 24 and 180 nM in chemotaxis and binding assay, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.73 mL | 113.67 mL | 227.35 mL |
| 0.5 mM | 4.55 mL | 22.73 mL | 45.47 mL |
| 1 mM | 2.27 mL | 11.37 mL | 22.73 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.55 mL |
*The above data is based on the productmolecular weight 439.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13380 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 439.86 |
| Formula | C21H21ClF3N3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 226226-39-7 |
| SMILES | O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3 |
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