Temsirolimus (Torisel)
目录号: A10906
mTOR 抑制剂
Temsirolimus 是一种特定的 mTOR 抑制剂,它干扰合成调节肿瘤细胞增殖、生长和存活的蛋白质。
Discription | Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells. | |||||
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Cell Research |
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目录号 | A10906 |
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分子式 | C56H87NO16 |
分子量 | 1030.3 |
CAS号 | 162635-04-3 |
SMILES | C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C\C=C\[C@H](C[C@H](C(=O)[C@H]([C@H](/C(=C\[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OC(=O)C(C)(CO)CO)C)/C)O)OC)C)C)/C)OC |
其他名称 | CCI-779 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 60 mg/mL (58.24 mM) | |
Water | Insoluble | ||
Ethanol | 67 mg/mL (65.03 mM) | ||
In vivo | 2% DMSO+30% PEG 300 +2% Tween 80+ddH2O | 6 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 9.71 mL | 48.53 mL | 97.06 mL |
0.5 mM | 1.94 mL | 9.71 mL | 19.41 mL |
1 mM | 0.97 mL | 4.85 mL | 9.71 mL |
5 mM | 0.19 mL | 0.97 mL | 1.94 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2