Temsirolimus (Torisel)

Name: Temsirolimus (Torisel)
SKU: A10906

目录号: A10906

mTOR 抑制剂

Temsirolimus (Torisel) Chemical Structure

CAS NO. 162635-04-3

Temsirolimus (Torisel)是mTOR的特异性抑制剂，会干扰调节肿瘤细胞增殖，生长和存活的蛋白质的合成。

库存：现货

规格	价格	数量
10 mg	￥ 420.00
25 mg	￥ 980.00
50 mg	￥ 1,750.00
200 mg	￥ 4,200.00
10mM * 1mL in DMSO	￥ 770.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Temsirolimus (Torisel)是mTOR的特异性抑制剂，会干扰调节肿瘤细胞增殖，生长和存活的蛋白质的合成。

靶点信息

mTOR (Cell-free assay)
1.76 μM

溶解度 *

In vitro (25°C)	DMSO	60 mg/mL (58.24 mM)
	Water	Insoluble
	Ethanol	67 mg/mL (65.03 mM)
In vivo	2% DMSO+30% PEG 300 +2% Tween 80+ddH2O	6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	9.71 mL	48.53 mL	97.06 mL
0.5 mM	1.94 mL	9.71 mL	19.41 mL
1 mM	0.97 mL	4.85 mL	9.71 mL
5 mM	0.19 mL	0.97 mL	1.94 mL

*The above data is based on the productmolecular weight 1030.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10906
作用机制	Inhibitor (抑制剂)
M. Wt	1030.3
Formula	C56H87NO16
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	162635-04-3
Synonyms	CCI-779
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C\C=C\[C@H](C[C@H](C(=O)[C@H]([C@H](/C(=C\[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OC(=O)C(C)(CO)CO)C)/C)O)OC)C)C)/C)OC