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Tenofovir Disoproxil Fumarate

Tenofovir Disoproxil Fumarate

Name: Tenofovir Disoproxil Fumarate
SKU: A10909

目录号: A10909

nucleotide reverse transcriptase 抑制剂

Product Citations (1)

Tenofovir Disoproxil Fumarate Chemical Structure

CAS NO. 202138-50-9

Tenofovir Disoproxil Fumarate属于一类抗逆转录病毒药物，其通过与天然底物脱氧腺苷5’-三磷酸盐竞争以及整合到DNA后终止DNA链抑制HIV reverse transcriptase活性。

库存：现货

规格	价格	数量
10 mg	￥ 280.00
25 mg	￥ 525.00
50 mg	￥ 630.00
100 mg	￥ 882.00
10mM * 1mL in DMSO	￥ 350.00

或

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产品详情

生物活性

Tenofovir Disoproxil Fumarate属于一类抗逆转录病毒药物，其通过与天然底物脱氧腺苷5’-三磷酸盐竞争以及整合到DNA后终止DNA链抑制HIV reverse transcriptase活性。

靶点信息

HIV reverse transcriptase (Cell-free assay)

溶解度 *

In vitro	DMSO	88 mg/mL (138.47 mM)
	Water	Insoluble
	Ethanol	39 mg/mL (61.36 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.74 mL	78.68 mL	157.35 mL
0.5 mM	3.15 mL	15.74 mL	31.47 mL
1 mM	1.57 mL	7.87 mL	15.74 mL
5 mM	0.31 mL	1.57 mL	3.15 mL

*The above data is based on the productmolecular weight 635.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10909
作用机制	Inhibitor (抑制剂)
M. Wt	635.51
Formula	C19H30N5O10P.C4H4O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	202138-50-9
Synonyms	Viread
SMILES	C[C@H](CN1C=NC2=C1N=CN=C2N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C.C(=C/C(=O)O)\C(=O)O