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Tenofovir (Viread)属于一类称为核苷逆转录酶抑制剂（NRTIs）的药物。它通过减少血液中的HIV含量起作用。
靶点信息
| Reverse transcriptase | ||||
| In vitro (25°C) | DMSO | Warmed: 4 mg/mL (13.92 mM) | |
| Water | 2 mg/mL (6.96 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.82 mL | 174.09 mL | 348.19 mL |
| 0.5 mM | 6.96 mL | 34.82 mL | 69.64 mL |
| 1 mM | 3.48 mL | 17.41 mL | 34.82 mL |
| 5 mM | 0.7 mL | 3.48 mL | 6.96 mL |
*The above data is based on the productmolecular weight 287.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10908 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 287.2 |
| Formula | C9H14N5O4P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 147127-20-6 |
| SMILES | C[C@H](CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O |
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