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Tenovin-6

目录号: A12305
p53 activator
Tenovin-6 是 tenovin-1 的类似物。Tenovin-6 在体外抑制纯化的人类 SIRT1SIRT2SIRT3 的蛋白去乙酰化酶活性,其 IC50 值分别为 21、10 和 67 微摩尔。
Grouped product items
规格 价格 库存 数量
1mg
¥210.00
现货
2mg
¥315.00
现货
5mg
¥455.00
现货
10mg
¥560.00
现货
25mg
¥1,050.00
现货
50mg
¥1,645.00
现货
100mg
¥2,835.00
现货
500mg
¥6,790.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Tenovin-6发表的1篇文献
  • Igase M,, .et al. , Exp Cell Res, 2019, Dec 28:111810 PMID: 31891684
  • 生物活性
    Discription Tenovin-6 is a analog of tenovin-1. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 values of 21, 10, and 67 uM, respectively.
    Targets
    Target Value
    产品信息
    目录号 A12305
    分子式 C25H34N4O2S
    分子量 454.6
    CAS号 1011557-82-6
    SMILES CC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)NC(=O)CCCCN(C)C
    其他名称 Tenovin6, Tenovin 6
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 87 mg/mL (191.36 mM)
    Water Warmed: 87 mg/mL (191.36 mM)
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22 mL 109.99 mL 219.97 mL
    0.5 mM 4.4 mL 22 mL 43.99 mL
    1 mM 2.2 mL 11 mL 22 mL
    5 mM 0.44 mL 2.2 mL 4.4 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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