TEPP-46

Name: TEPP-46
SKU: A16279
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A16279

PKM2 activator

TEPP-46 是一种强效且选择性的重组丙酮酸激酶 M2（PKM2）激活剂，其半最大激活浓度（AC50 值）为 92 nM，对丙酮酸激酶 M1（PKM1）、丙酮酸激酶 L（PKL）和丙酮酸激酶 R（PKR）几乎没有活性。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥525.00	现货
10mg	¥945.00	现货
25mg	¥1,680.00	现货
50mg	¥2,555.00	现货
100mg	¥3,850.00	现货
500mg	¥8,505.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

TEPP-46 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and little or no activity versus PKM1, PKL and PKR.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16279
分子式	C17H16N4O2S2
分子量	372.46
CAS号	1221186-53-3
SMILES	O=C1C(N(C)C2=C3SC(S(C)=O)=C2)=C3C=NN1CC4=CC=CC(N)=C4
其他名称	ML-265
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	73 mg/mL (195.99 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.85 mL	134.24 mL	268.49 mL
0.5 mM	5.37 mL	26.85 mL	53.7 mL
1 mM	2.68 mL	13.42 mL	26.85 mL
5 mM	0.54 mL	2.68 mL	5.37 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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