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Tetrandrine (Fanchinine)是一种钙通道阻滞剂。粉防己碱具有抗炎和抗纤维化作用,使粉防己碱及其相关化合物潜在地用于治疗肺矽肺,肝硬化和类风湿性关节炎。
靶点信息
Calcium channel | ||||
In vitro | DMSO | Warmed: 1 mg/mL (1.6 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (3.21 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.06 mL | 80.28 mL | 160.57 mL |
0.5 mM | 3.21 mL | 16.06 mL | 32.11 mL |
1 mM | 1.61 mL | 8.03 mL | 16.06 mL |
5 mM | 0.32 mL | 1.61 mL | 3.21 mL |
*The above data is based on the productmolecular weight 622.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10921 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 622.8 |
Formula | C38H42N2O6 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 518-34-3 |
Synonyms | Fanchinine, Hanfangchin A, NSC 77037, S,S-(+)-Tetrandrine, Sinomenine A, TTD, Tetrandrin, d-Tetrandr |
SMILES | CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC |
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