TG-101348 (Fedratinib, SAR302503)
目录号: A11082
JAK2/FLT3 抑制剂
TG-101348 是一种口服生物利用度高的、ATP竞争性的、选择性的 Janus-associated kinase 2 抑制剂,具有潜在的抗肿瘤活性。
Discription | TG-101348 is an orally bioavailable, ATP-competitive and selective inhibitor of Janus-associated kinase 2 with potential antineoplastic activity. | |||||
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Targets |
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Cell Research |
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目录号 | A11082 |
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分子式 | C27H36N6O3S |
分子量 | 524.7 |
CAS号 | 936091-26-8 |
SMILES | CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4 |
其他名称 | SAR302503,TG101348,TG101348 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 90 mg/mL (171.53 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.06 mL | 95.29 mL | 190.59 mL |
0.5 mM | 3.81 mL | 19.06 mL | 38.12 mL |
1 mM | 1.91 mL | 9.53 mL | 19.06 mL |
5 mM | 0.38 mL | 1.91 mL | 3.81 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2