Tipifarnib S enantiomer

目录号: A21787

FTase inhibitor

Tipifarnib S enantiomer

Tipifarnib S enantiomer Chemical Structure

CAS NO. 192185-71-0

Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.

库存: 现货

规格 价格 数量
5 mg
¥ 1,351.00
10 mg
¥ 2,324.00
50 mg
¥ 6,888.00
100 mg
¥ 13,783.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.43 mL 102.17 mL 204.33 mL
0.5 mM 4.09 mL 20.43 mL 40.87 mL
1 mM 2.04 mL 10.22 mL 20.43 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21787
作用机制 Inhibitor (抑制剂)
M. Wt 489.4
Formula C27H22Cl2N4O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 192185-71-0
Synonyms (S)-(-)-R-115777, R115777, R 115777; IND-58359 S enantiomer, IND58359, IND 58359
SMILES O=C1N(C)C2=C(C=C([C@](C3=CC=C(Cl)C=C3)(N)C4=CN=CN4C)C=C2)C(C5=CC=CC(Cl)=C5)=C1

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