产品详情
Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM. Tipifarnib S enantiomer is the less active isomer.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.43 mL | 102.17 mL | 204.33 mL |
0.5 mM | 4.09 mL | 20.43 mL | 40.87 mL |
1 mM | 2.04 mL | 10.22 mL | 20.43 mL |
5 mM | 0.41 mL | 2.04 mL | 4.09 mL |
*The above data is based on the productmolecular weight 489.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A21787 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 489.4 |
Formula | C27H22Cl2N4O |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 192185-71-0 |
Synonyms | (S)-(-)-R-115777, R115777, R 115777; IND-58359 S enantiomer, IND58359, IND 58359 |
SMILES | O=C1N(C)C2=C(C=C([C@](C3=CC=C(Cl)C=C3)(N)C4=CN=CN4C)C=C2)C(C5=CC=CC(Cl)=C5)=C1 |
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