Tivozanib (AV-951)

Name: Tivozanib (AV-951)
SKU: A10101
Price: 175 CNY
Rating: 5 (7 reviews)

目录号: A10101

VEGFR 抑制剂

7 篇发表文献

Tivozanib（AV-951）是一种口服 VEGF 受体酪氨酸激酶抑制剂，旨在抑制所有三种 VEGF 受体。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥805.00	现货
50mg	¥1,225.00	现货
100mg	¥2,380.00	现货
200mg	¥4,585.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Tivozanib (AV-951)发表的7篇文献

Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932

Majid Momeny, .et al. , Life Sci, 2021, Dec 15;287:120100 PMID: 34715143

Majid Momeny, .et al. , Eur J Pharmacol, 2020, 882:173298

Majid Momeny, .et al. , Sci Rep, 2017, 7: 45954 PMID: 28383032

Majid Momeny, .et al. , Sci Rep, 2017, 7: 44075 PMID: 28287096

Nicholas A. Manieri, .et al. , J Clin Invest, 2015, Sep 1; 125(9): 3606-3618 PMID: 26280574

Usui T, .et al. , Acta Physiol (Oxf), 2014, 211, 385-394 PMID: 24612679

生物活性

Discription

Tivozanib (AV-951) is an oral VEGF receptor tyrosine kinase inhibitor that is designed to inhibit all three VEGF receptors.

Targets

Target	Value

产品信息

目录号	A10101
分子式	C22H19ClN4O5
分子量	454.9
CAS号	475108-18-0
SMILES	CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	19 mg/mL (41.76 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.98 mL	109.91 mL	219.83 mL
0.5 mM	4.4 mL	21.98 mL	43.97 mL
1 mM	2.2 mL	10.99 mL	21.98 mL
5 mM	0.44 mL	2.2 mL	4.4 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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