TM5441
目录号: A19369
PAI-1 inhibitor
TM5441 是一种口服生物可用的抗纤溶酶原激活物抑制剂-1 (PAI-1)，其 IC50 值介于 13.9 至 51.1 μM 之间，并且在多种人类癌症细胞系中诱导内源性凋亡。
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生物活性
| Discription | TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines. |
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产品信息
| 目录号 | A19369 |
|---|---|
| 分子式 | C21H17ClN2O6 |
| 分子量 | 428.82 |
| CAS号 | 1190221-43-2 |
| SMILES | ClC1=CC=C(NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O)C(C(O)=O)=C1 |
| 其他名称 | M-5441; TM 5441; BMS-790052; BMS-790052; BMS790052; EBP 883; EBP-883; EBP883 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 83 mg/mL (193.55 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.32 mL | 116.6 mL | 233.2 mL |
| 0.5 mM | 4.66 mL | 23.32 mL | 46.64 mL |
| 1 mM | 2.33 mL | 11.66 mL | 23.32 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1190221-43-2 | 1190221-43-2 供应商 | 1190221-43-2 花费 | 1190221-43-2 生产商 | 订购 1190221-43-2 | 1190221-43-2 代理商