TNP-470
目录号: A14014
MetAP-2 inhibitor
TNP 470 是 Fumagillin 的一种类似物,体外显示出强大的抗血管生成活性。已显示可抑制 MetAP-2(甲硫氨酸氨肽酶类型 II)。
Discription | TNP 470 is an analog of Fumagillin that displays potent antiangiogenic activity in vitro. Shown to inhibit MetAP-2 (methionine aminopeptidase type II ). | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A14014 |
---|---|
分子式 | C19H28CINO6 |
分子量 | 401.88 |
CAS号 | 129298-91-5 |
SMILES | CC(=CC[C@H]1[C@](O1)(C)C2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)NC(=O)CCl)OC)C |
其他名称 | TNP470, TNP 470, O-(Chloroacetyl-carbamoyl) Fumagillol, NSC 642492, AGM-1470 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2