Toceranib phosphate
目录号: A15263
c-Kit/VEGFR2/PDGFRβ 抑制剂
托瑟拉尼磷酸盐是一种激酶抑制剂,通过抑制KIT、血管内皮生长因子受体2和PDGFRβ,具有抗肿瘤和抗血管生成活性。
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重要通知:仅供研究使用。我们不向患者销售。
c-Kit/VEGFR2/PDGFRβ 抑制剂
重要通知:仅供研究使用。我们不向患者销售。
Discription | Toceranib phosphate is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ. | ||
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Targets |
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目录号 | A15263 |
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分子式 | C22H28FN4O6P |
分子量 | 494.45 |
CAS号 | 874819-74-6 |
SMILES | CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O |
其他名称 | SU 11654, PHA 291639, SU11654, SU-11654, PHA-291639, PHA291639 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 2 mg/mL (4.04 mM) | |
Water | 2 mg/mL (4.04 mM) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.22 mL | 101.12 mL | 202.24 mL |
0.5 mM | 4.04 mL | 20.22 mL | 40.45 mL |
1 mM | 2.02 mL | 10.11 mL | 20.22 mL |
5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2