Tofogliflozin (hydrate)

Name: Tofogliflozin (hydrate)
SKU: A17860
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A17860

SGLT2 抑制剂

托格列净水合物（CSG-452水合物）是一种强效且高度特异性的钠/葡萄糖共转运体2（SGLT2）抑制剂，其半抑制浓度（IC50）为2.9纳摩尔，对人类、大鼠和小鼠SGLT2的Ki值分别为2.9纳摩尔、14.9纳摩尔和6.4纳摩尔。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥560.00	现货
10mg	¥945.00	现货
25mg	¥1,855.00	现货
50mg	¥3,185.00	现货
100mg	¥4,760.00	现货
200mg	¥6,790.00	现货
500mg	¥9,975.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription	Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2.

产品信息

目录号	A17860
分子式	C22H28O7
分子量	404.45
CAS号	1201913-82-7
SMILES	O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]21OCC3=C2C=C(CC4=CC=C(CC)C=C4)C=C3.O
其他名称	CSG-452 hydrate, CSG452, CSG 452
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	82 mg/mL (202.74 mM)
	Water	4 mg/mL (9.88 mM)
	Ethanol	82 mg/mL (202.74 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.72 mL	123.62 mL	247.25 mL
0.5 mM	4.94 mL	24.72 mL	49.45 mL
1 mM	2.47 mL	12.36 mL	24.72 mL
5 mM	0.49 mL	2.47 mL	4.94 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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