Tomivosertib
目录号: A20407
MNK1/MNK2 inhibitor
Tomivosertib(eFT508)是一种效力强大、高度选择性且口服生物利用度高的 MNK1 和 MNK2 抑制剂,对这两种亚型的 IC50 值为 1-2 nM。
Discription | Tomivosertib (eFT508) is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms. | |||||
---|---|---|---|---|---|---|
Targets |
|
|||||
Cell Research |
|
目录号 | A20407 |
---|---|
分子式 | C17H20N6O2 |
分子量 | 340.38 |
CAS号 | 1849590-01-7 |
SMILES | O=C(C1=C(C)C=C(NC2=NC=NC(N)=C2)C(N13)=O)NC43CCCCC4 |
其他名称 | eFT508, eFT 508, eFT-508 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 12 mg/mL (35.25 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.38 mL | 146.89 mL | 293.79 mL |
0.5 mM | 5.88 mL | 29.38 mL | 58.76 mL |
1 mM | 2.94 mL | 14.69 mL | 29.38 mL |
5 mM | 0.59 mL | 2.94 mL | 5.88 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2