Tomivosertib

目录号: A20407
MNK1/MNK2 inhibitor
Tomivosertib(eFT508)是一种效力强大、高度选择性且口服生物利用度高的 MNK1MNK2 抑制剂,对这两种亚型的 IC50 值为 1-2 nM。
Grouped product items
规格 价格 库存 数量
1mg
¥315.00
现货
5mg
¥1,050.00
现货
10mg
¥1,645.00
现货
25mg
¥3,290.00
现货
50mg
¥4,795.00
现货
100mg
¥6,825.00
现货
10mM * 1mL in DMSO
¥1,260.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription Tomivosertib (eFT508) is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A20407
分子式 C17H20N6O2
分子量 340.38
CAS号 1849590-01-7
SMILES O=C(C1=C(C)C=C(NC2=NC=NC(N)=C2)C(N13)=O)NC43CCCCC4
其他名称 eFT508, eFT 508, eFT-508
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 12 mg/mL (35.25 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.38 mL 146.89 mL 293.79 mL
0.5 mM 5.88 mL 29.38 mL 58.76 mL
1 mM 2.94 mL 14.69 mL 29.38 mL
5 mM 0.59 mL 2.94 mL 5.88 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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