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Topotecan HCl (Hycamtin)

Topotecan HCl (Hycamtin)

Name: Topotecan HCl (Hycamtin)
SKU: A10939

目录号: A10939

DNA topoisomerase I 抑制剂

Topotecan HCl (Hycamtin) Chemical Structure

CAS NO. 119413-54-6

Topotecan HCl (Hycamtin)是一种化学治疗剂，是拓扑异构酶抑制剂。

库存：现货

规格	价格	数量
50 mg	￥ 875.00
100 mg	￥ 1,155.00
200 mg	￥ 1,750.00
10mM * 1mL in DMSO	￥ 385.00

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生物活性

Topotecan HCl (Hycamtin)是一种化学治疗剂，是拓扑异构酶抑制剂。

溶解度 *

In vitro (25°C)	DMSO	87 mg/mL (189.99 mM)
	Water	87 mg/mL (189.99 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.84 mL	109.19 mL	218.39 mL
0.5 mM	4.37 mL	21.84 mL	43.68 mL
1 mM	2.18 mL	10.92 mL	21.84 mL
5 mM	0.44 mL	2.18 mL	4.37 mL

*The above data is based on the productmolecular weight 457.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10939
作用机制	Inhibitor (抑制剂)
M. Wt	457.9
Formula	C23H23N3O5 .HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	119413-54-6
Synonyms	Hycamtin
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl