Topotecan
目录号: A16815
Topoisomerase 抑制剂
Topotecan 是一种抗肿瘤药物,用于治疗卵巢癌,其作用机制是抑制 DNA 拓扑异构酶。
Discription | Topotecan is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases. | |||||
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Targets |
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Cell Research |
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目录号 | A16815 |
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分子式 | C23H23N3O5 |
分子量 | 421.45 |
CAS号 | 123948-87-8 |
SMILES | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O |
其他名称 | SKF104864, SKF 104864, SKF-104864, NSC 609669, NSC609669, NSC-609669 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 76 mg/mL (180.33 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.73 mL | 118.64 mL | 237.28 mL |
0.5 mM | 4.75 mL | 23.73 mL | 47.46 mL |
1 mM | 2.37 mL | 11.86 mL | 23.73 mL |
5 mM | 0.47 mL | 2.37 mL | 4.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2