TP0463518
目录号: A20183
PHD inhibitor
TP0463518 是一种强效的低氧诱导因子脯氨酸羟化酶（PHDs）抑制剂，其对人类PHD2的Ki值为5.3 nM。
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生物活性
| Discription | TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. |
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产品信息
| 目录号 | A20183 |
|---|---|
| 分子式 | C20H18ClN3O6 |
| 分子量 | 431.83 |
| CAS号 | 1558021-37-6 |
| SMILES | ClC(C=C1)=CC=C1OC2=NC=C(CN3C(C(C(NCC(O)=O)=O)=C(O)CC3)=O)C=C2 |
| 其他名称 | TP 0463518, TP-0463518 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 34 mg/mL (78.73 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.16 mL | 115.79 mL | 231.57 mL |
| 0.5 mM | 4.63 mL | 23.16 mL | 46.31 mL |
| 1 mM | 2.32 mL | 11.58 mL | 23.16 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1558021-37-6 | 1558021-37-6 供应商 | 1558021-37-6 花费 | 1558021-37-6 生产商 | 订购 1558021-37-6 | 1558021-37-6 代理商