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TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.76 mL | 103.82 mL | 207.65 mL |
| 0.5 mM | 4.15 mL | 20.76 mL | 41.53 mL |
| 1 mM | 2.08 mL | 10.38 mL | 20.76 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.15 mL |
*The above data is based on the productmolecular weight 481.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12655 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 481.58 |
| Formula | C27H35N3O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2018300-62-2 |
| Synonyms | TPOP-146; TPOP 146 |
| SMILES | COC1=CC(OC)=CC(C2=CC(C(N[C@H]3CCCN(C)C3)=O)=C(OCCN(C(CC)=O)C4)C4=C2)=C1 |
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