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TRC 051384，属于取代的2-丙烯-1-酮类，是热休克蛋白70（HSP70）的有效诱导剂。HSP70的诱导是应激细胞的自然反应，可保护神经元细胞免受各种损伤，包括急性缺血。
| In vitro | DMSO | 86 mg/mL (184.72 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (10.74 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.48 mL | 107.4 mL | 214.8 mL |
| 0.5 mM | 4.3 mL | 21.48 mL | 42.96 mL |
| 1 mM | 2.15 mL | 10.74 mL | 21.48 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
*The above data is based on the productmolecular weight 465.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16053 |
|---|---|
| 作用机制 | Inducer (诱导剂) |
| M. Wt | 465.54 |
| Formula | C25H31N5O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 867164-40-7 |
| Synonyms | TRC051384, TRC-051384 |
| SMILES | O=C(C1=CC=C(N/C(O)=N/CCN2CCOCC2)C=C1)/C([H])=C([H])/C3=NC(N4CCOCC4)=CC=C3 |
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