Trk-IN-3
目录号: A19298
pan-Trk inhibitor
Trk-IN-3 是一种在细胞测试中效力强大的全面 Trk 抑制剂,其半抑制浓度(IC50)分别为 TrkA 8.4 nM、TrkB 6.2 nM 和 TrkC 2.2 nM。具有抗高敏感性效果。
Discription | Trk-IN-3 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 8.4 nM, 6.2 nM and 2.2 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect. | ||
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目录号 | A19298 |
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分子式 | C20H19F5N4O4 |
分子量 | 474.38 |
CAS号 | 1873373-33-1 |
SMILES | NC1=C(O[C@@H]2C(F)(F)CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C2)C=C(C(NC)=O)C=N1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2