Trk-IN-4

目录号: A19277
pan-Trk inhibitor
Trk-IN-4 (PF-6683324 异构体) 是一种在细胞测试中的强效 全Trk抑制剂,其半抑制浓度(IC50)分别为 TrkA 1.9 nM、TrkB 2.6 nM 和 TrkC 1.1 nM。具有抗高敏感性效果。
Grouped product items
规格 价格 库存 数量
1mg
¥280.00
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5mg
¥700.00
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10mg
¥1,260.00
现货
25mg
¥2,835.00
现货
50mg
¥4,795.00
现货
100mg
¥8,400.00
现货
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生物活性
Discription Trk-IN-4 (PF-6683324 isomer) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect.
Targets
Target Value
产品信息
目录号 A19277
分子式 C24H23F4N5O4
分子量 521.46
CAS号 1799788-94-5
SMILES O=C(N)C1=C(O[C@H]2CCN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C[C@H]2F)N=CC(C4=CN(C)C=N4)=C1
其他名称 PF-6683324 isomer
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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