Trk Receptors
Catalog No. | Inhibitor Name | TrkA | TrkB | TrkC | Trk receptor | Other |
---|---|---|---|---|---|---|
A11059 | BMS-754807 | ** | *** | Insulin Receptor,IGF-1R,Met | ||
A16238 | GW441756 | **** | ||||
A16259 | Sitravatinib (MGCD516) | *** | * | DDR2,EPHA3,Axl | ||
A13877 | ANA-12 | * | ||||
A13730 | GNF-5837 | ** | * | ** | ||
A15801 | Entrectinib (RXDX-101) | ALK,ROS1 | ||||
A10053 | Tyrphostin AG 879 | * | Her2 | |||
A10715 | Danusertib (PHA-739358) | * | Aurora A, Abl, RET, FGFR1, Aurora C, Aurora B | |||
A15494 | LM22A-4 | * | ||||
A15974 | Larotrectinib (LOXO-101) sulfate | |||||
A16123 | 7,8-Dihydroxyflavone |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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LM22A-4
Catalog No. A15494 -
7,8-Dihydroxyflavone
Catalog No. A16123 TrkB 激动剂7,8-Dihydroxyflavone是一种选择性的酪氨酸激酶受体B(神经营养因子/原肌球蛋白受体激酶B;TrkB)激动剂,可用于帮助识别和区分由TrkB激活介导的生理效应和细胞信号通路。涉及神经保护,记忆,血管舒张和高血压。 了解更多