Tropisetron HCL

Name: Tropisetron HCL
SKU: A14375

目录号: A14375

5-HT3 receptor 拮抗剂

Tropisetron HCL Chemical Structure

CAS NO. 105826-92-4

Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂，对5-HT3受体的IC50为70.1±0.9 nM。

库存：现货

规格	价格	数量
100 mg	￥ 700.00
500 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 441.00

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生物活性

Tropisetron HCL是选择性的5-HT3受体拮抗剂和α7烟碱样受体激动剂，对5-HT3受体的IC50为70.1±0.9 nM。

溶解度 *

In vitro	DMSO	34 mg/mL (105.97 mM)
	Water	45 mg/mL (140.26 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.17 mL	155.86 mL	311.71 mL
0.5 mM	6.23 mL	31.17 mL	62.34 mL
1 mM	3.12 mL	15.59 mL	31.17 mL
5 mM	0.62 mL	3.12 mL	6.23 mL

*The above data is based on the productmolecular weight 320.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14375
作用机制	Antagonist (拮抗剂)
M. Wt	320.81
Formula	C17H21ClN2O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	105826-92-4
Synonyms	Novaban, SDZ-ICS 930
SMILES	CN1C2CCC1CC(C2)OC(=O)C3=CNC4=CC=CC=C43.Cl