产品详情

生物活性

Tubacin (tubulin acetylation inducer)是一种高效且选择性强，可逆，可透过细胞的HDAC6抑制剂，IC50为4 nM。

靶点信息

HDAC6 (Cell-free assay)
4 nM

溶解度 *

In vitro (25°C)	DMSO	93 mg/mL (128.83 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.85 mL	69.26 mL	138.52 mL
0.5 mM	2.77 mL	13.85 mL	27.7 mL
1 mM	1.39 mL	6.93 mL	13.85 mL
5 mM	0.28 mL	1.39 mL	2.77 mL

*The above data is based on the productmolecular weight 721.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10954
作用机制	Inhibitor (抑制剂)
M. Wt	721.9
Formula	C41H43N3O7S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	537049-40-4
SMILES	C1[C@@H](O[C@@H](O[C@@H]1C2=CC=C(C=C2)CO)C3=CC=C(C=C3)NC(=O)CCCCCCC(=O)NO)CSC4=NC(=C(O4)C5=CC=CC=C5)C6=CC=CC=C6